Initial dose: At least 150 units/kg; frequently, 300 units/kg is used for procedures estimated to last less than 60 minutes or 400 units/kg for those estimated to last longer than 60 minutes.
-Consult the latest guidelines regarding duration and intensity of anticoagulation for the indicated conditions.
-Dosage and administration must be individualized according to the results of suitable laboratory tests.
-Prevention of clotting in arterial and cardiac surgery.
-Total body perfusion for open-heart surgery.