Effects of prolonged steroid use on the human body

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IN THIS ARTICLE
  • What are Steroids?
  • Different Types of Steroids
  • Side Effects of Prolonged Steroid Abuse
  • When to Seek Medical Care for Steroid Abuse
  • Steroid Abuse Diagnosis
  • Steroid Addiction Treatment
  • Medical Treatment for Steroid Abuse
  • Other Therapy for Steroid Abuse
  • Steroid Abuse Prevention
  • Prognosis for Steroid Abuse
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Side Effects of Prolonged Steroid Abuse

UV exposure would also lead to the activation of receptors for epidermal growth factor, IL-1, and TNF-α in keratinocytes and fibroblasts, which then activates signaling kinases throughout the skin via an unknown mechanism. [7] The nuclear transcription factor activator protein, AP-1, which controls the transcription of matrix metalloproteinases (MMP), is expressed and activated. MMP-1 is a major metalloproteinases for collagen degradation. This entire process is aided by the presence of reactive oxygen species that inhibits protein-tyrosine phosphatases via oxidation, thereby resulting in the up-regulation of the above-mentioned receptors. Another transcription factor NF-κB, which is also activated by UV light, also increases the expression of MMP-9.

Effects of prolonged steroid use on the human body

effects of prolonged steroid use on the human body

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