Prednisone steroid and weight gain

Corticosteroids can produce reversible hypothalamic- pituitary adrenal (HPA) axis suppression with the potential for corticosteroid insufficiency after withdrawal of treatment. Adrenocortical insufficiency may result from too rapid withdrawal of corticosteroids and may be minimized by gradual reduction of dosage. This type of relative insufficiency may persist for up to 12 months after discontinuation of therapy; therefore, in any situation of stress occurring during that period, hormone therapy should be reinstituted. If the patient is receiving steroids already, dosage may have to be increased.

During conventional pharmacologic dose corticosteroid therapy, ACTH production is inhibited with subsequent suppression of cortisol production by the adrenal cortex. Recovery time for normal HPA activity is variable depending upon the dose and duration of treatment. During this time the patient is vulnerable to any stressful situation. Although it has been shown that there is considerably less adrenal suppression following a single morning dose of prednisolone (10 mg) as opposed to a quarter of that dose administered every 6 hours, there is evidence that some suppressive effect on adrenal activity may be carried over into the following day when pharmacologic doses are used. Further, it has been shown that a single dose of certain corticosteroids will produce adrenocortical suppression for two or more days. Other corticoids, including methylprednisolone, hydrocortisone, Prednisone, and prednisolone, are considered to be short acting (producing adrenocortical suppression for 1¼ to 1½ days following a single dose) and thus are recommended for alternate day therapy.

Prednisone can interact with a number of different drugs, including OTC and some herbal preparations. Let your doctor know about all the medications you take. The most common interactions are with NSAIDs , anti-infectives (such as ciprofloxacin , some HIV medicines ), immune suppressants , diuretics ("water” pills), and anticoagulants (blood thinners), but there are many more. If you are worried that some of your medicines may be interacting, talk with your doctor or pharmacist. Alternatively, you can use our drug interaction checker .

Prednisone steroid and weight gain

prednisone steroid and weight gain

Media:

prednisone steroid and weight gainprednisone steroid and weight gainprednisone steroid and weight gainprednisone steroid and weight gainprednisone steroid and weight gain

http://buy-steroids.org